List PLR Content Marketing Tennessee: Avage Topical

Generic Name: tazarotene (Topical route)

taz-AR-oh-teen

Commonly used brand name(s)

In the U.S.

Avage

Tazorac

Available Dosage Forms:

Gel/Jelly

Cream

Therapeutic Class: Dermatological Agent

Chemical Class: Retinoid

Uses For Avage

Tazarotene is used to treat acne on the face and and to treat psoriasis.

It works to help clear acne on the face partly by keeping skin pores clear. It works in the treatment of psoriasis by making the skin less red and reducing the number and size of lesions of the skin.

This medicine is available only with your doctor's prescription.

Before Using Avage

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies of this medicine have been done only in adult patients, and there is no specific information comparing use of tazarotene in children up to 12 years of age (gel) and up to 18 years of age (cream) with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether or not they work in exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing the use of tazarotene in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	X	Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of tazarotene

This section provides information on the proper use of a number of products that contain tazarotene. It may not be specific to Avage. Please read with care.

It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Read the patient information that will come with your medicine.

For acne—Before applying tazarotene to acne areas of the skin, wash the skin with a mild soap or cleanser and warm water, then gently pat dry. Wait at least 20 to 30 minutes before applying this medicine.

For acne or psoriasis—Do not use this medicine in or around the eyes or lips, or inside of the nose. Spread the medicine away form these areas when applying

Do not apply this medicine to windburned or sunburned skin or on open wounds.

When using tazarotene, apply medicine to dry skin. If skin has just been washed and dried, wait at least 20 to 30 minutes before applying this medicine. Applying to wet or damp skin may cause skin irritation.

Apply a thin layer of this medicine only to lesions of psoriasis on the body or areas on face prone to developing acne. Rub medicine in gently and well. Wash medicine off skin areas not intended to be treated.

After applying the medicine, wash your hands to remove any medicine that might remain on them.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel):
- For acne:
  - Adults and children 12 years of age and older—Apply 0.1% tazarotene to clean, dry affected areas of the face once a day, usually in the evening or at bedtime.
  - Children up to 12 years of age—Use and dose must be determined by the doctor.
- For psoriasis:
  - Adults and children 12 years of age and older—Apply 0.05% or 0.1% tazarotene to dry affected areas of the body once a day, usually in the evening or at bedtime. Do not treat a larger area of the skin than your doctor tells you to treat.
  - Children up to 12 years of age—Use and dose must be determined by the doctor.

For topical dosage form (cream):
- For psoriasis:
  - Adults and children 18 years of age and older—Apply 0.05% or 0.1% tazarotene to dry affected areas of the body once a day, usually in the evening or at bedtime. Do not treat a larger area of the skin than your doctor tells you to treat.
  - Children up to 18 years of age—Use and dose must be determined by the doctor.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Avage

If you think that you may be pregnant, stop using the medicine immediately and check with your doctor.

If you are using this medicine to treat acne of the face, your condition may seem to worsen at first before it begins to improve in about 4 weeks. Check with your doctor if your condition does not improve within 8 to 12 weeks.

If your are using this medicine to treat psoriasis, scaly patches on skin may begin to improve in about 1 to 4 weeks but redness may take longer to improve. Check with your doctor if your condition becomes worse.

Do not cover the treated area with a bandage.

When using tazarotene, do not use skin products such as abrasive soaps or cleansers; alcohol-containing products; cosmetics or soaps that dry the skin; hair products that are irritating, such as permanents or hair removal products; skin products containing spices, limes, or other ingredients that may make the skin more sensitive to the sun; or other topical medicine for the skin on the same area as tazarotene, unless otherwise directed. To do so may cause severe irritation of the skin.

Ask your doctor before taking vitamin A supplements by mouth while using this medicine.

During treatment with this medicine, avoid exposing the treated areas to sunlight when possible, since the skin may be more likely to become sunburned. Do not use a sunlamp.

Some people who use this medicine may become more sensitive to wind or cold weather, as well as to sunlight. Avoiding exposure to these conditions by using sunscreen products with a sun protection factor (SPF) of 15 or more and wearing protective clothing will help protect your skin against becoming too dry, irritated, or sunburned.

Avage Side Effects

It is likely that your skin may become irritated with normal use of this medicine. You should not stop using tazarotene unless your skin becomes too red, dry, puffy, or otherwise irritated. If severe irritation occurs, contact your doctor.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Burning or stinging of the skin (severe)

changes in color of treated skin

deep grooves or lines in skin

dryness, itching, peeling, or redness of the skin (severe)

pain or swelling of treated skin

skin rash (in patients with psoriasis only)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning or stinging after application

dryness, itching, peeling, or redness of the skin (mild)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Avage Topical side effects (in more detail)

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Monday, October 17, 2016

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